GLP-1, SIBO & the Microbiome

The Medications & the Research

Mechanism of action, the evidence for benefit, and an honest look at where the evidence for burden actually sits.

Gut & Microbiome Impact

How SCFA production regulates the same pathway these medications target, and why microbiome status isn't incidental to outcomes.

SIBO & Risk vs Benefit

The motility mechanism behind SIBO risk, and a framework for weighing risk against benefit with each patient.

Key Therapies, Three Moments

What to prioritise for patients not yet on a GLP-1, currently taking one, or coming off one.

Karly Raven, BHSc

Naturopath · SIBO Specialist · Practitioner Educator

Karly holds a Bachelor of Health Science in Naturopathy and is a member of the Naturopaths and Herbalists Association of Australia. She practises online to patients Australia-wide.

Karly is the founder of Nourished Gut Clinic and creator of the Feed Forward methodology and the SIBO Restore Diet™, the staged dietary framework she now teaches to practitioners. She works with practitioners and patients navigating IBS, SIBO, IBD and chronic gut conditions, specialising in gastrointestinal health and seeing a high volume of patients with IBS, SIBO, bowel disease and generalised microbiome dysbiosis. She mentors health practitioners through karlyraven.com.

For this session, Karly leads the teaching, from the mechanism and the evidence through to the therapy considerations for patients at each stage of GLP-1 treatment.

Carla Wrenn

Naturopath, BHSc · Guest Expert

Carla is an integrative naturopath, nutritionist and herbalist who has been in practice since 2001. She holds a Bachelor of Health Science in Naturopathy plus diplomas in Naturopathy, Nutrition, Herbal Medicine and Classical Homeopathy, alongside postgraduate study in Integrative Oncology, Autoimmune Disease and Functional Medicine. In 2023 Carla was named Practitioner of the Year by the Australian Traditional Medicine Society. She co-owns Peninsula Herbal Dispensary & Naturopathic Clinic on the Mornington Peninsula, where her work focuses on complex and chronic disease. For this session, Carla brings both her clinical expertise and her own personal experience with GLP-1 therapy, followed by a moderated conversation and the full Q&A from the live session.

Before Starting

Gut and microbiome optimisation, screening considerations, addressing existing motility or infection issues.

While Taking

Managing nausea and GI side effects, supporting motility, maintaining fibre and diversity through treatment.

Coming Off

Supporting the transition, addressing rebound risk, rebuilding what treatment may have depleted.

The Full Replay

The complete 90-minute training, recorded live on 1 October 2026. Watch at your own pace and come back to it whenever a GLP-1 patient walks in.

Clinical Desk Reference

PDF download

Seventeen clinical tools across the treatment arc, from a SIBO risk stratifier and baseline panel to drug effect vs overgrowth, breath testing on therapy and a monitoring schedule. Built to keep open in consult.

Presentation Slides

PDF download

The complete 62-slide deck with the full reference list, so you can go straight to the research.

Guest Segment & Q&A

Carla Wrenn's clinical and personal perspective on GLP-1 therapy, plus the complete practitioner Q&A.